Blood Brothers: A Family’s Mission to Detect Cancer Early

Epigeneres Biotech was founded in 2012 by Dr. Vinay Kumar Tripathi and Ashish Tripathi. The founding of Epigeneres Biotech was driven by the Tripathi family’s commitment to revolutionize cancer detection and treatment. Their personal experiences and professional expertise converged to address the pressing need for early cancer detection methods.

Dr. Vinay Kumar Tripathi 

Dr. Vinay Kumar Tripathi is an accomplished professional serving as the Chairman of Epigeneres. Based in Thane, Maharashtra, India, Dr. Tripathi has been at the helm of the organization since April 2012, marking over 12 years of dedicated leadership and innovation in the field of biotechnology. An alumnus of two prestigious institutions, IIT BHU (Banaras Hindu University) and the Indian Institute of Technology, Roorkee, Dr. Tripathi’s academic background is steeped in excellence.

Ashish Tripathi

Ashish Tripathi is a visionary leader in the pharmaceutical and healthcare sectors, currently serving as the Chief Executive Officer of Tzar Labs. Based in Mumbai, Maharashtra, India, Ashish has been at the forefront of groundbreaking work in molecular diagnostics and medicine since April 2020. His extensive experience includes leadership positions at renowned organizations such as Edelweiss Capital, Ernst & Young, and Avendus Capital. An alumnus of the Melbourne Business School, Ashish holds an MBA in Finance and Strategy. Prior to this, he earned a Bachelor of Arts with honors in Economics from St. Xavier’s College. 

The Founding Story

The founding story of Epigeneres Biotech is deeply personal and profoundly inspiring. It began with a tragedy that struck the family of Ashish Tripathi, who co-founded the company alongside their father, the late Dr. VK Tripathi. In 2018, their brother-in-law, Himanshu Roy, a high-ranking Indian police officer, succumbed to cancer after battling the disease for years. Roy’s untimely death, which followed a note citing his despair over the incurable nature of his illness, became the catalyst for the Tripathi family’s mission to revolutionize cancer detection.

Himanshu Roy’s words left a lasting impact on Ashish, particularly his observation that cancer had become a “disease of the rich,” inaccessible to many due to the high costs of treatment. Determined to address this disparity, the Tripathis envisioned a solution that could make cancer detection affordable, early, and accessible to everyone.

Growing Cells and Numbers: Biotech’s Booming Billion-Dollar Industry

The global biotechnology market has experienced significant growth in recent years. In 2023, the market was valued at approximately USD 1.55 trillion. Projections indicate that it will continue to expand at a compound annual growth rate (CAGR) of 13.96% from 2024 to 2030, reaching an estimated USD 4.61 trillion by 2034. (Grand View Research)

This growth is driven by several factors, including strong government support through initiatives aimed at modernizing regulatory frameworks, improving approval processes, and standardizing clinical studies. The increasing adoption of personalized medicine and the development of orphan drug formulations are also opening new avenues for biotechnology applications. Additionally, the COVID-19 pandemic has positively impacted the biotechnology market by propelling advancements in drug development and vaccine manufacturing.

The biotechnology sector encompasses various applications, including health, bioinformatics, food and agriculture, industrial processing, and environmental sustainability. Among these, the health segment holds a significant share, driven by the rising prevalence of chronic diseases and the subsequent demand for advanced therapeutics and diagnostics.

Regionally, North America dominates the biotechnology market, accounting for a substantial revenue share. This dominance is attributed to the presence of major industry players, extensive research and development activities, and substantial healthcare expenditures. However, the Asia-Pacific region, particularly countries like India and China, is expected to witness the fastest growth. Factors such as increasing investments in research and development, a growing skilled workforce, and supportive government policies contribute to this regional expansion. (Polarismarketresearch)

Cancer: 0, Epigeneres: 1 – A Vision for Early Detection and Hope

Mission and Vision

Epigeneres Biotech is dedicated to revolutionizing cancer detection and treatment. Their mission centers on developing advanced genetic therapeutics and nutrigenomic formulations to address serious medical conditions, with a particular emphasis on early cancer detection and personalized medicine. The company’s vision is to transform cancer care by providing real-time, comprehensive, and swift diagnostic insights. By leveraging cutting-edge RNA biomarker technology, Epigeneres aims to detect cancer at its earliest stages, even before tumor formation, thereby significantly improving patient outcomes and survival rates. 

Problems They Solve

Epigeneres addresses the critical challenge of late-stage cancer detection, which often leads to limited treatment options and lower survival rates. Traditional diagnostic methods may fail to identify cancer until it has progressed to advanced stages. To solve this problem, Epigeneres has developed a blood test capable of detecting cancerous stem cells before tumors form, with nearly 100% accuracy. This early detection enables timely intervention, increasing the likelihood of successful treatment and reducing mortality rates.

Business Model

The company’s business model focuses on the development and commercialization of innovative diagnostic tools and therapeutics. By collaborating with specialized molecular diagnostic companies like Singapore-based Tzar Labs, Epigeneres co-develops proprietary technologies for early cancer detection. They offer these diagnostic services to healthcare providers and patients, generating revenue through test sales and related services. Additionally, Epigeneres invests in research and development to expand their product portfolio, aiming to introduce more advanced solutions in the biotechnology sector.

Stem the Tide: The HrC Test and Other Breakthroughs

Epigeneres Biotech is at the forefront of biotechnology, providing innovative products and solutions that transform healthcare. From cutting-edge diagnostic tools to advanced nutrigenomic supplements, the company is committed to improving lives through science and technology.

1. NovaGenere: The Ultimate Nutrigenomic Supplement

NovaGenere is a breakthrough supplement that combines the power of nature and science to deliver unparalleled health benefits. This plant-based formulation is enriched with potent antioxidants and bioactive compounds, targeting various aspects of cellular health.

Key Ingredients:

• Resveratrol and Pterostilbene: These two powerful antioxidants neutralize free radicals, reduce oxidative stress, and support healthy aging.
• Phytoextracts: Includes saponins, proanthocyanidins, tannins, flavonoids, catechins, and anthocyanins to enhance cellular protection.
• Oleuropein and Anthocyanins: Additional antioxidants that amplify the product’s efficacy in fighting oxidative stress and inflammation.

Benefits:

1. Super Antioxidant Properties: Protects against chronic diseases caused by oxidative stress by removing harmful toxins and free radicals.
2. Cellular Rejuvenation: Repairs and rejuvenates cells, supporting youthful energy and vigor.
3. Immunity Booster: Enhances the body’s defense mechanisms by stimulating interleukins like INF-⍺, increasing natural killer cell activity.
4. Anti-Inflammatory: Neutralizes pro-inflammatory cytokines and improves immune responses to combat infection and inflammation.
5. Anti-Aging: Slows cellular aging by activating Sirt-1, a gene linked to longevity and vitality.
6. Enhanced Bioavailability: Its dual delivery system ensures that critical nutrients are effectively absorbed for optimal benefits.

NovaGenere is ideal for anyone seeking a holistic supplement that supports immunity, reduces aging effects, and boosts overall vitality.

2. nCurcu: Advanced Curcumin for Complete Health

nCurcu is a cutting-edge curcumin supplement formulated to overcome the common challenges of bioavailability. Curcumin, a naturally occurring compound in turmeric, is celebrated for its numerous health benefits but often struggles with poor absorption. nCurcu solves this issue with a unique formulation that ensures maximum bioavailability and potency.

Key Features:

• High Potency: Delivers curcumin in a highly absorbable form, maximizing its therapeutic potential.
• Stability: Overcomes oxidative instability for consistent and reliable benefits.

Benefits:

1. Antioxidant Protection: Shields cells from damage caused by free radicals, helping prevent oxidative stress.
2. Cognitive Enhancement: Supports brain health by improving memory and cognitive function, particularly in aging individuals.
3. Heart Health: Improves endothelial function, which is essential for cardiovascular health and maintaining proper blood flow.
4. Anti-Inflammatory Action: Reduces inflammation, offering relief for conditions like arthritis, gut inflammation, and other inflammatory disorders.
5. Gastrointestinal Support: Restores gut health by reducing inflammation and enhancing microbial diversity.
6. Skin Benefits: Improves skin hydration, elasticity, and overall appearance while countering signs of aging.

nCurcu is a versatile supplement for those aiming to enhance their physical and cognitive health. Its applications range from improving heart health to addressing skin concerns, making it a well-rounded addition to anyone’s wellness routine.

3. The HrC Test: Early Cancer Detection

The HrC test offered by Epigeneres is a monumental breakthrough in the field of diagnostics. It provides unparalleled accuracy in detecting cancer at its earliest stages.

What Makes the HrC Test Unique?

• Detects cancer at stage 0 or stage 1, well before symptoms arise.
• Uses a simple, non-invasive blood test instead of traditional biopsies.
• Offers over 99% accuracy, making it one of the most reliable tests on the market.
• Predicts cancer risk for up to 12 months in advance, empowering individuals to take preventive measures.

This test is ideal for anyone seeking proactive health monitoring. 

Code Crackers: The Science Behind Catching Cancer Early

At the core of their technology is their expertise in cancer diagnostics. The HrC test, developed in collaboration with Tzar Labs, is a pioneering blood test that detects cancer stem cells before tumor formation. Unlike conventional diagnostics that rely on imaging or biopsies, the HrC test focuses on pluripotent stem cells that undergo epigenetic transformations into cancer stem cells. These transformed cells are mobilized into the bloodstream and can be detected at stage 0 or stage 1, long before symptoms appear. The test utilizes genetic markers to identify these cells with over 99% accuracy, offering unparalleled precision in diagnosing cancer early. Additionally, the HrC test predicts cancer risk for the next 12 months, empowering patients and physicians to take preventive action. This non-invasive, cost-effective approach redefines cancer detection and significantly enhances survival rates.

Nutrigenomics

Another key area of innovation is nutrigenomics, the study of how nutrition interacts with genes to influence health. Epigeneres leverages this science to design supplements like NovaGenere and nCurcu, which work at the cellular level to improve overall well-being. Their nutrigenomic products are formulated with advanced phytoextracts and bioactive compounds that target gene expression, supporting cellular repair and rejuvenation.

NovaGenere incorporates antioxidants like resveratrol and pterostilbene, which are known to activate the Sirt-1 gene. This gene is a critical regulator of cellular health and longevity, playing a role in slowing down aging and repairing DNA damage. The product also includes a dual delivery system that ensures these potent antioxidants are absorbed efficiently, maximizing their therapeutic benefits. By reducing oxidative stress and inflammation, NovaGenere protects cells from damage and supports immune function.

Similarly, nCurcu addresses the challenges of curcumin’s poor bioavailability by using a specialized formulation that enhances its absorption and stability. Curcumin, derived from turmeric, has long been known for its anti-inflammatory and antioxidant properties. With advanced bioavailability, nCurcu delivers these benefits more effectively, helping to reduce systemic inflammation, improve cognitive function, and promote skin and heart health.

Epigeneres also harnesses the potential of epigenetics, the study of how external factors influence gene expression without altering the underlying DNA sequence. Epigenetics forms the foundation of their products and technologies, allowing them to create solutions that reprogram cellular behavior. For example, their products target pathways that regulate inflammation, oxidative stress, and cellular senescence. By modulating these pathways, Epigeneres products enhance the body’s ability to heal, repair, and maintain optimal health.

Winning the Genome Game: Epigeneres’ Impact in Biotech

In May 2021, Epigeneres Biotech, in collaboration with Singapore-based Tzar Labs, announced the development of an early detection cancer test. Such a breakthrough has the potential to revolutionize cancer diagnostics by enabling earlier interventions and improving patient outcomes. 

The HrC Test is a groundbreaking blood test that evaluates rare stem cell markers to detect cancer at its earliest stages, even before tumor formation. This innovation has been a cornerstone of Epigeneres’ success, offering a minimally invasive and highly accurate diagnostic tool. The test has gained significant attention for its ability to detect a wide range of cancers, including solid tumors and hematological malignancies, at stage zero, a feat that few diagnostic tools have achieved.

Epigeneres Biotech is also supported by a robust advisory board and executive team, which includes leaders and visionaries such as Ray Kurzweil, co-founder of Singularity University and a prominent figure at Google, and Gregory C. Simon, the former executive director of the White House Cancer Moonshot Task Force. This esteemed team underscores the company’s commitment to leveraging world-class expertise to drive its mission​.

Cash Flow That Counts: Funding the Fight Against Cancer

Epigeneres Biotech has successfully raised $7.85 million in equity funding through two rounds. The company’s funding journey began with a Series A round in April 2018, which secured $1.9 million at a valuation of $43.8 million. This round included notable corporate investors such as Torrent Pharma and HCG, alongside angel investors like Viraj Mehta, Venkatchalam Ramaswamy, and Dilip Bhai S Mehta. The funds were instrumental in setting the foundation for the company’s growth and scaling its pioneering technologies.

In December 2021, Epigeneres completed its Series B funding round, raising $6 million at a valuation of $122 million. This round was led by institutional investors such as Shri Padam Ventures and VM Spice, with participation from corporate entities like LetsVenture, Kotak Investment Advisors, and East River Advisors. Angel investors, including Moez Daya and Ashish Kacholia, also contributed.

Financially, Epigeneres has shown steady growth in revenue. For the fiscal year 2022-23, the company reported revenue of ₹3.5 crore, up from ₹1.9 crore in 2021-22. This growth trajectory reflects increasing market adoption of its diagnostic solutions and expanding client base. Over the years, Epigeneres has demonstrated resilience and adaptability, growing its revenue from modest beginnings of ₹0.3 crore in FY 2020-21.

Ending on a High Note: A Company That Lives to Save Lives

Epigeneres Biotech is revolutionizing cancer diagnostics with its innovative approach to early detection. By leveraging advanced RNA biomarker technology, their HrC Test can detect cancer at Stage Zero, long before tumor formation. This minimally invasive blood test is a game-changer in healthcare, offering hope for earlier interventions and improved patient outcomes. 

The company’s focus on personalized healthcare extends to its nutrigenomic products, designed to enhance overall wellness and prevent age-related conditions. Epigeneres has built a reputation as a leader in biotechnology through consistent innovation and strategic collaborations. Their partnership with Tzar Labs has been instrumental in pushing the boundaries of cancer diagnostics.

For anyone looking to understand how innovation drives impactful change, Epigeneres Biotech stands as a prime example. To learn more about their work and explore other insights into the startup ecosystem, check out more articles on Venture Kites.